The CNIH2/3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to Cnih2, and CNIH3. This antibody recognizes Rat antigen. The CNIH2/3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitization. CNIH2 also blocks CACNG8-mediated resensitization of AMPA receptors